Does anyone know how to give a very, very stubborn five-year-old medicine? My daughter and I were up at 4am and at the ER with a suspected appendicitis. They kept us there for hours to get fluids in her and to observe her. We were sent home “on alert” for appendicitis, but with a suspected UTI as well. She is supposed to take antibiotics, one teaspoon two times a day. She will never, ever take medicine. Luckily, she almost never has to. One time she had a fever, we had to give her a suppository (no, they don’t make antibiotics into a suppository). Anyway, we struggled and struggled for 45 min tonight just to get her to take it. She gets herself soooo worked up over it. I get afraid she will throw up because she gets so upset. We refuse to hold her down to get her to take it. We want her to do it herself. It is so stressful negotiating with her. It doesn’t matter what it tastes like. If you tell her it is medicine, she doesn’t want it. Any suggestions?